Explain how gallstones develop (pathogenises).

CASE STUDY
A 43-year-old woman is experiencing intermittent colicky-type pain in the right upper quadrant of the abdomen, radiating to the right scapular region. The onset was approximately 1 week earlier. In the last few days, she has had nausea and vomiting, increasing in the last 24 hours. The pain is more severe today, and the emesis is bile colored. Vital signs are the following: temperature, 99.6° F; pulse, 96; respiration, 26; and blood pressure, 144/92 mm Hg. Her skin is warm and dry, slightly jaundiced. The patient is somewhat obese and has been on oral contraceptives for 15 years. Cholelithiasis is suggested. A CT scan of the gallbladder confirms the presence of stones in the gallbladder and also in the common bile duct. Serum bilirubin is elevated. The patient is scheduled for laparoscopic surgery.
Discussion Questions
Explain how gallstones develop (pathogenises).
Which type of person would be most likely to develop gallstones

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