A 50-year-old man with a history of depression began treatment with a monoamine oxidase inhibitor (MAOI) concurrently with a tapering schedule from a selective serotonin reuptake inhibitor (SSRI). Six hours post-administration of the MAOI, he exhibits tachycardia, elevated body temperature, and signs of confusion and agitation. What is the most important step in management?
- Implement supportive care.
- Cease administration of both the SSRI and the MAOI immediately.
- Administer benzodiazepines for sedation.
- Administer serotonin antagonists.
- Increase hydration with intravenous fluids.
The correct Answer is Cease administration of both the SSRI and the MAOI immediately.
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