A nurse practitioner prescribes amitriptyline (Elavil), a tricyclic antidepressant, to a patient for the management of neuropathic pain. The patient returns complaining of dizziness and lightheadedness upon standing. Which of the following mechanisms is most likely responsible for these symptoms?
- H1 antagonism
- Alpha-1 receptor antagonism
- Alpha-2 receptor antagonism
- Serotonin reuptake inhibition
- Muscarinic receptor antagonism
The correct Answer is Alpha-1 receptor antagonism
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NURS 6521 Final Exam Question 35 / NURS 6521 Advanced Pharmacology